Vip Viprakasit Selected Research

SP-420

12/2017

Safety and pharmacokinetics of the oral iron chelator SP-420 in β-thalassemia.

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Vip Viprakasit Research Topics

Disease

51	Thalassemia 05/2024 - 08/2002
33	Iron Overload 05/2024 - 09/2003
20	beta-Thalassemia (Cooley's Anemia) 01/2023 - 07/2002
11	Anemia 05/2024 - 03/2004
8	Hemolytic Anemia 01/2024 - 12/2004
8	alpha-Thalassemia 03/2009 - 02/2002
5	Hemolysis 10/2022 - 08/2002
5	Infections 01/2018 - 03/2008
4	Hemoglobinopathies 12/2020 - 04/2004
3	Fever (Fevers) 10/2023 - 01/2009
3	Pyruvate Kinase Deficiency of Red Cells 09/2023 - 10/2022
3	Sickle Cell Anemia (Hemoglobin S Disease) 03/2023 - 01/2016
3	Disease Progression 01/2023 - 09/2006
3	Fatigue 01/2023 - 01/2019
3	Siderosis 06/2015 - 03/2010
3	Iron Deficiencies 03/2009 - 07/2004
3	Hemochromatosis (Bronze Diabetes) 08/2005 - 09/2003
2	Respiratory Tract Infections (Respiratory Tract Infection) 10/2023 - 08/2023
2	Proteinuria 08/2023 - 12/2017
2	Chronic Disease (Chronic Diseases) 01/2023 - 06/2014
2	Arthralgia (Joint Pain) 10/2022 - 01/2020
2	Headache (Headaches) 10/2022 - 10/2022
2	Pain (Aches) 10/2022 - 01/2020
2	Hemosiderosis 01/2022 - 04/2010
2	Osteoporosis 01/2021 - 10/2013
2	Gallstones (Gallstone) 01/2021 - 01/2018
2	Metabolic Bone Diseases (Osteopenia) 01/2021 - 10/2013
2	Splenomegaly 01/2020 - 01/2009
2	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 01/2016 - 02/2004
2	Hemophagocytic Lymphohistiocytosis (Hemophagocytic Syndrome) 08/2015 - 11/2005
1	Diarrhea 08/2023
1	Pharyngitis (Sore Throat) 08/2023
1	Cholecystitis 01/2023
1	Pulmonary Hypertension 01/2023
1	Edema (Dropsy) 01/2023
1	Nausea 10/2022
1	Ovarian Cysts (Ovarian Cyst) 10/2022
1	Renal Colic 10/2022
1	COVID-19 10/2021
1	Body Weight (Weight, Body) 01/2020
1	Hypertension (High Blood Pressure) 01/2020
1	Dizziness (Lightheadedness) 01/2020
1	Hyperuricemia 01/2020
1	Neoplasms (Cancer) 01/2019
1	Thrombosis (Thrombus) 01/2018
1	Fanconi Syndrome (Syndrome, Fanconi) 12/2017
1	Severe Dengue 08/2015

Drug/Important Bio-Agent (IBA)

42	IronIBA 05/2024 - 09/2003
19	Deferasirox FDA Link 10/2023 - 03/2010
18	Hemoglobins (Hemoglobin)IBA 01/2023 - 02/2002
12	GlobinsIBA 01/2024 - 02/2002
11	Ferritins (Ferritin)IBA 01/2023 - 07/2004
9	Hemoglobin EIBA 01/2022 - 06/2007
7	Chelating AgentsIBA 12/2017 - 11/2009
7	alpha-GlobinsIBA 03/2010 - 02/2004
6	HepcidinsIBA 01/2023 - 09/2003
5	Deferoxamine (Desferal)FDA LinkGeneric 04/2021 - 01/2014
5	beta-Globins (beta Globin)IBA 03/2018 - 05/2004
4	Proteins (Proteins, Gene)FDA Link 05/2024 - 05/2004
4	CreatinineIBA 05/2024 - 01/2011
4	luspaterceptIBA 07/2023 - 01/2020
4	metal transporting protein 1 (ferroportin)IBA 01/2021 - 09/2003
4	Hemoglobin Constant SpringIBA 08/2015 - 02/2002
3	TabletsIBA 10/2023 - 01/2022
3	Hemoglobin HIBA 01/2020 - 02/2004
3	DeferiproneIBA 01/2016 - 11/2009
2	mitapivatIBA 09/2023 - 10/2022
2	Transaminases (Aminotransferases)IBA 08/2023 - 01/2017
2	Transferrin (beta 2 Transferrin)IBA 01/2023 - 01/2016
2	Pyruvate KinaseIBA 01/2023 - 10/2022
2	Alanine Transaminase (SGPT)IBA 10/2022 - 01/2011
2	Transcription Factors (Transcription Factor)IBA 01/2021 - 03/2014
2	Vitamin D FDA LinkGeneric 01/2021 - 10/2013
2	3-iodo-4-azido-N-hexadecylsalicylamideIBA 08/2015 - 11/2005
2	Glycated Hemoglobin (Glycosylated Hemoglobin)IBA 04/2014 - 01/2014
2	Initiator Codon (Start Codon)IBA 01/2014 - 01/2005
2	DNA (Deoxyribonucleic Acid)IBA 08/2013 - 03/2009
2	4,5- dihydro- 2- (2- hydroxy- 3- (3,6,9- trioxadecyloxy)phenyl)- 4- methyl- 4- thiazolecarboxylic acidIBA 04/2012 - 04/2011
2	Codon (Codons)IBA 09/2007 - 03/2004
1	thiaclopridIBA 10/2023
1	Aspartate Aminotransferases (Aspartate Transaminase)IBA 10/2022
1	Triglycerides (Triacylglycerol)IBA 10/2022
1	AntigensIBA 10/2021
1	betibeglogene autotemcelIBA 10/2021
1	Activins (Activin)IBA 10/2021
1	LigandsIBA 10/2021
1	Sickle HemoglobinIBA 04/2020
1	Glucose (Dextrose)FDA LinkGeneric 01/2020
1	desferrithiocinIBA 12/2017
1	SP-420IBA 12/2017
1	Biomarkers (Surrogate Marker)IBA 01/2017
1	Growth Differentiation Factor 15IBA 01/2017

Therapy/Procedure

15	Therapeutics 01/2024 - 11/2005
14	Chelation Therapy (Therapy, Chelation) 05/2024 - 11/2009
10	Blood Transfusion (Blood Transfusions) 08/2023 - 07/2002
5	Splenectomy 01/2020 - 06/2013
2	Erythrocyte Transfusion 07/2023 - 12/2020
1	Intrauterine Blood Transfusion 01/2023
1	Prenatal Care (Care, Prenatal) 10/2021
1	Hematopoietic Stem Cell Transplantation 01/2020